It’s been just a few weeks since boxing legend and activist Mohamand Ali died of sepsis, a condition that still remains greatly a mystery to many outside and inside healthcare.
In our previous worked focusing upon sepsis, we learned several discrepancies exist in incidence and mortality reporting due to the host of definitions and terminologies used for sepsis in the field.
Formally, sepsis definitions have been largely unchanged for more than two decades, that is, until the recent publication of “Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)“.
There are now only two identified stages of sepsis: Sepsis and septic shock, as the new sepsis-3 definitions are designed to apply only to patients with life-threatening organ dysfunction caused by a dysregulated host response to infection. “Severe” sepsis is no longer used in the terminology and the milder stage of sepsis that was identified as “sepsis” by SIRS+ (Systemic Inflammatory Response Syndrome) criteria is no longer recognized. With this new definition, “sepsis” now best correlates with the old version’s status of severe sepsis.
Seeking clarification, we decided to contact Dr. Claypool, MD, Medical Director, POC Advisor, Wolters Kluwer for his thoughts on these recent definition changes and how they may impact physicians and the patients.
(Editor’s note: To hear audio excerpts of this interview, click on the media player buttons that run throughout this article.)